产地 | 进口/国产 |
保存条件 | 低温冷藏 |
品牌 | 上海富雨 |
货号 | WM-23MX137 |
用途 | 科研 |
组织来源 | 见详情 |
细胞形态 | 见详情 |
是否是肿瘤细胞 | |
保质期 | 见详情 |
器官来源 | 见详情 |
免疫类型 | 见详情 |
品系 | 见详情 |
生长状态 | 见详情 |
物种来源 | 见详情 |
包装规格 | 1×10?cells/T25或1mL冻存管 |
是否进口 | 是 |
,
to SQSTM1. This conclusion was sup- ported by the observation that the BCL10 polyubiquitination-deficient mutant, K31, 63R (first reported by Jonathan Ashwell’s group at the National Cancer Institute) does not interact with SQSTM1 or LC3, and is not degraded post-TCR stimu- lation. The SQSTM1-BCL10 interac- tion is most likely mediated by BCL10 K63-polyubiquitin chains binding to the C-terminal UBA domain of SQSTM1. Recruitment of LC3+ autophagosomes to sites of BCL10-SQSTM1 clusters pre- sumably depends on the SQSTM1 LC3 interacting region (LIR)